The term "lean mass hyper-responder" was coined by software engineer David Feldman on July 3, 2017 while posting in his low-carb diet blog: "Cholesterol Code." The blog post called "Are you a Lean Mass Hyper-responder?" quickly circulated through the low-carb community.
As background, the original term "hyper-responder" was already used by dietary professionals for years prior to Feldman's blog post. And in dietary literature, a "hyper-responder" is someone who adopts a low-carb diet, then experiences dramatic cholesterol elevation. So when Feldman wrote his 2017 blog article, he co-opted "hyper-responder," and crafted his new term "lean mass hyper-responder" to describe what he believes is a metabolically unique sub-set of all hyper-responders. Specifically, some hyper-responders begin a low-carb diet while already in possession of a very lean body mass. And yet in spite of this, they still --quite counter-intuitively-- respond with extreme cholesterol elevation. Additionally, these subjects experience a marked decrease in triglycerides, while exhibiting excellent metabolic health. The entire phenomenon defied a long-standing metabolic theory called "The Lipid Energy Model," presenting a scientific conundrum for Feldman.
Feldman believed that all this was a significant observation worth exploring. And his efforts eventually led to a 2023 research project called "The Lean Mass Hyper-Responder Study" led by Dr. Matthew Budoff and Dr. Nicholas Norwitz at Lundquist, UCLA.
As background, the original term "hyper-responder" was already used by dietary professionals for years prior to Feldman's blog post. And in dietary literature, a "hyper-responder" is someone who adopts a low-carb diet, then experiences dramatic cholesterol elevation. So when Feldman wrote his 2017 blog article, he co-opted "hyper-responder," and crafted his new term "lean mass hyper-responder" to describe what he believes is a metabolically unique sub-set of all hyper-responders. Specifically, some hyper-responders begin a low-carb diet while already in possession of a very lean body mass. And yet in spite of this, they still --quite counter-intuitively-- respond with extreme cholesterol elevation. Additionally, these subjects experience a marked decrease in triglycerides, while exhibiting excellent metabolic health. The entire phenomenon defied a long-standing metabolic theory called "The Lipid Energy Model," presenting a scientific conundrum for Feldman.
Feldman believed that all this was a significant observation worth exploring. And his efforts eventually led to a 2023 research project called "The Lean Mass Hyper-Responder Study" led by Dr. Matthew Budoff and Dr. Nicholas Norwitz at Lundquist, UCLA.
IN A SENTENCE: "Steve has always been a tall, skinny, beanpole of a guy. And then when he went on the carnivore diet, he was still skinny, but his cholesterol went through the roof. His doc said that overall he's pretty healthy, so he might just be a lean mass hyper-responder."
by Innocent Byproduct December 13, 2023
Get the Lean Mass Hyper-Responder mug.Referring to a beverage that is used to get one intoxicated. Generally consists of Codeine Syrup, soda (Sprite), and candy (commonly Jolly Ranchers). The mixture often is purple in color due to the Codeine syrup which gives it its other name "Purple Drank"
After drinking lean she was very intoxicated
by Coolkakizz July 2, 2023
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Get the Spring leaning mug.When you have dinner with the dog and it's not human food but in fact it is the dogs food that u and ur double date doggie duo that is what is on the menu for supper
by Anjunetta Rumagina November 25, 2021
Get the Lean cuisine mug.Lean is the most protective and caring person. He would often make you lagh and is very attractive. This person is normally very strong and has a greate body. He is sosialy awkward around strangers. This is a tipe of person that would ceep a secret. They are very trustworthy and loyal. These people are party people and love to have people they know aroud them. Lean's can handel anything and can ceep there emotions umder controll. These people somethimes have anger issuse but use it for the better. They are very adventurice and love the outdoors. They ussaly get into trubble or do nauty thing. They are known as busy people. They are outdoor people and know alot. Anay girl is very lucky to have sutch a hunk for a boyfriend and should never lose them. To attract a Lean you have to have delisious and a lot of food.
Lean is a handsom guy !
by Bakgat December 1, 2021
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When a man decides to lean upon another man’s woman for physical support. This tactic may be used to steal said woman from said man.
“Hey man, I’m feeling really insecure about that guy over there leaning on my gf like that.”
“Yeah you should, he’s doing The Gavin Lean.”
“Yeah you should, he’s doing The Gavin Lean.”
by Doodledobot May 2, 2022
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